产品货号:
Z22149
中文名称:
NLRP2抗体
英文名称:
Anti-NLRP2 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
| 抗体名称 | Anti-NLRP2 Antibody |
| 指标别名 | CLR19.9;NALP2;NBS1;NLRP2;PAN1;PYPAF2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,ELISA |
| 基因名称 | NLRP2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human NALP2/NLRP2 recombinant protein (Position:F9-K190). |
| 实际分子量 | 121KD |
| 成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | NACHT,LRR and PYD domains-containing protein 2 is a protein that in humans is encoded by the NLRP2 gene.It is mapped to 19q13.42.This gene is a member of the nucleotide-binding and leucine-rich repeat receptor (NLR) family,and is predicted to contain an N-terminal pyrin effector domain (PYD),a centrally-located nucleotide-binding and oligomerization domain (NACHT) and C-terminal leucine-rich repeats (LRR).Members of this gene family are thought to be important regulators of immune responses.This gene product interacts with components of the IkB kinase (IKK) complex,and can regulate both caspase-1 and NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells) activity.The pyrin domain is necessary and sufficient for suppression of NF-kB activity.An allelic variant (rs147585490) has been found that is incapable of blocking the transcriptional activity of NF-kB.Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Uniprot ID | Q9NX02 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot(WB) 1:500~2000 (ELISA): 1:100~1000 |
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